KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CHAT
All Species:
3.64
Human Site:
T553
Identified Species:
6.67
UniProt:
P28329
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P28329
NP_066266.3
748
82536
T553
L
H
R
R
L
V
P
T
Y
E
S
A
S
I
R
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001109211
626
70697
Q447
A
Y
Y
R
I
Y
R
Q
A
C
A
T
Y
E
S
Dog
Lupus familis
XP_543902
686
76910
N507
F
Q
E
G
R
V
D
N
I
R
S
A
T
P
E
Cat
Felis silvestris
Mouse
Mus musculus
Q03059
641
71834
N462
F
Q
E
G
R
V
D
N
I
R
S
A
T
P
E
Rat
Rattus norvegicus
P32738
640
71845
N461
F
Q
E
G
R
V
D
N
I
R
S
A
T
P
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509108
643
72737
N464
F
E
E
G
R
V
D
N
I
R
S
A
T
P
E
Chicken
Gallus gallus
Q90YJ9
640
72605
N461
F
D
E
G
R
V
D
N
I
R
S
A
T
A
E
Frog
Xenopus laevis
Q7ZXE1
659
74538
Q480
F
Q
M
A
F
L
R
Q
Y
G
K
T
T
A
T
Zebra Danio
Brachydanio rerio
B2ZGJ1
637
71821
R458
E
G
R
V
D
N
I
R
S
S
T
P
E
A
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P07668
721
81310
T529
L
Y
G
R
L
V
A
T
Y
E
S
A
S
T
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P32756
627
71299
L448
H
Y
K
T
H
G
H
L
V
S
T
Y
E
S
A
Sea Urchin
Strong. purpuratus
XP_001185550
675
75787
R496
Y
E
S
G
S
T
R
R
F
Q
E
G
R
V
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32796
670
77223
L491
F
K
Y
L
K
R
Q
L
P
T
Y
E
A
A
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
37.8
77.9
N.A.
74.7
74.7
N.A.
68.4
66
24
57
N.A.
37.5
N.A.
29.2
46.3
Protein Similarity:
100
N.A.
55.7
82.4
N.A.
79.1
79
N.A.
76.5
74
40.6
68.8
N.A.
56.1
N.A.
45.1
62.4
P-Site Identity:
100
N.A.
6.6
20
N.A.
20
20
N.A.
20
20
6.6
6.6
N.A.
73.3
N.A.
0
0
P-Site Similarity:
100
N.A.
26.6
26.6
N.A.
26.6
26.6
N.A.
26.6
26.6
20
13.3
N.A.
80
N.A.
20
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
27
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
8
0
0
8
0
8
0
8
54
8
31
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% C
% Asp:
0
8
0
0
8
0
39
0
0
0
0
0
0
0
8
% D
% Glu:
8
16
39
0
0
0
0
0
0
16
8
8
16
8
39
% E
% Phe:
54
0
0
0
8
0
0
0
8
0
0
0
0
0
0
% F
% Gly:
0
8
8
47
0
8
0
0
0
8
0
8
0
0
0
% G
% His:
8
8
0
0
8
0
8
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
8
0
8
0
39
0
0
0
0
8
0
% I
% Lys:
0
8
8
0
8
0
0
0
0
0
8
0
0
0
0
% K
% Leu:
16
0
0
8
16
8
0
16
0
0
0
0
0
0
8
% L
% Met:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
8
0
39
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
8
0
8
0
0
8
0
31
0
% P
% Gln:
0
31
0
0
0
0
8
16
0
8
0
0
0
0
0
% Q
% Arg:
0
0
16
24
39
8
24
16
0
39
0
0
8
0
16
% R
% Ser:
0
0
8
0
8
0
0
0
8
16
54
0
16
8
16
% S
% Thr:
0
0
0
8
0
8
0
16
0
8
16
16
47
8
8
% T
% Val:
0
0
0
8
0
54
0
0
8
0
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
24
16
0
0
8
0
0
24
0
8
8
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _